Chemical Product N, N-Diisopropylethylamine CAS 7087-68-5 with Best Price
Product Description
Product Name: N,N-Diisopropylethylamine
CAS 7087-68-5
MOQ:1KG
| Melting point | <-50 °C (lit.) |
| Boiling point | 127 °C (lit.) |
| Density | 0.742 g/mL at 25 °C (lit.) |
| Vapor pressure | 31 mmHg ( 37.7 °C) |
| Refractive index | n20/D 1.457 |
| Fp | 6 °C |
| Storage temp. | Store below +30°C. |
| Solubility | miscible |
| Form | Liquid |
| Pka | 10.98±0.28(Predicted) |
| Specific Gravity | 0.755 (20/4ºC) |
| Color | APHA: <20 |
| PH | 12.3 (H2O, 20ºC)(as an emulsion) |
| Explosive limit | 0.7-6.3%(V) |
| Water Solubility | miscible |
| Packing | 200Kg/Drum |
Basic Information
- Product Name: N,N-Diisopropylethylamine (DIPEA)
- Chemical Formula: C8H19N
- Other Names: Diisopropylethylamine, Hünig’s Base, DIPEA
- Appearance: Colorless to light yellow clear liquid
- Odor: Strong amine-like odor
- Solubility: Miscible with organic solvents (e.g., dichloromethane, toluene); slightly soluble in water.
Physical and Chemical Properties
- Density: 0.74 g/cm³ (25°C)
- Melting Point: -46°C
- Boiling Point: 127-128°C
- Refractive Index: 1.412 (20°C)
- Flash Point: 27°C (closed cup)
- pKa (Conjugate Acid): ~11.2 (in water)
Chemical Properties
- Base Properties: As a tertiary amine, it acts as a moderate to strong organic base, capable of abstracting protons in acid-base reactions. Its steric hindrance (bulky isopropyl groups) makes it a “hindered base,” reducing its nucleophilicity while preserving basicity.
- Reduced Nucleophilicity: Due to steric bulk, the nitrogen atom is less accessible for nucleophilic attacks, making it suitable for reactions where base activity is needed without nucleophilic side reactions (e.g., alkylation, acylation).
- Solubility Characteristics: Its organic solubility allows it to function in non-aqueous reaction media, while its moderate basicity (weaker than sodium hydride but stronger than triethylamine) makes it versatile in organic synthesis.
Applications
- Organic Synthesis:
- Base in Condensation Reactions: Used in peptide synthesis, esterification, and amide formation to neutralize byproduct acids (e.g., HCl) and drive reactions forward.
- Hindered Base for Selective Deprotonation: Preferentially abstracts protons from less sterically hindered sites, useful in reactions like aldol condensations or enolate formations.
- Catalyst in Cyclization and Esterification: Promotes ring-closing reactions or facilitates ester synthesis under mild conditions.
- Pharmaceutical Industry:
- As a reagent in drug intermediate synthesis, especially for molecules sensitive to strong nucleophiles.
- Polymer Chemistry:
- Catalyst for urethane polymerization and epoxy resin curing.
- Electrochemistry:
- Used as a supporting electrolyte in some electrochemical reactions due to its good solubility in organic solvents.
Safety Considerations
- Hazard Class: Flammable liquid; causes skin and eye irritation; harmful if inhaled or ingested.
- Storage: Store in a cool, ventilated place, away from oxidizing agents and acids; keep containers sealed to prevent vapor release.
- Handling:
- Use in a fume hood to avoid inhaling vapors.
- Wear protective gloves and goggles; avoid skin/eye contact (flush with water immediately if exposed).
- Dispose of waste according to hazardous chemical protocols.
Comparison with Triethylamine (TEA)
| Property | DIPEA | Triethylamine (TEA) |
| Basicity (pKa) | ~11.2 | ~10.7 |
| Steric Hindrance | High (due to isopropyl groups) | Low (ethyl groups) |
| Nucleophilicity | Low | Moderate |
| Use Case | Reactions needing hindered base | General-purpose base |
| Solubility in Water | Slightly soluble | Moderately soluble |
| Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
| Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Quality is at the heart of everything we do. We source our raw materials from reputable suppliers and subject them to a rigorous testing process to ensure only the highest standards are met. Our state-of-the-art manufacturing facilities and advanced technologies enable us to produce chemicals that are not only of superior quality but also comply with global regulatory and safety standards.
Our business scope is wide, covering products in multiple fields, including but not limited to daily necessities raw materials, catalyst additives, etc. With rich industry experience and a professional procurement team, we have established long-term and stable cooperative relationships with many high-quality suppliers at home and abroad, and can ensure that we provide customers with high-quality and diversified products.
have a highly qualified and experienced professional team, including international trade experts, senior salesmen, logistics specialists, and after-sales service personnel. They are proficient in international trade processes and relevant laws and regulations, and can provide customers with a full range of one-stop services, from product procurement, order processing, customs declaration and inspection, logistics and transportation to after-sales service, ensuring that every link is efficient and smooth.
business network is spread all over the world, and has established long-term cooperative relationships with customers in many countries and regions such as Asia, Southeast Asia, and the Middle East. We always adhere to the business philosophy of “quality first, customer first”, and have won the trust and praise of customers with high-quality products and services, and established a good corporate image in the international market.
In the future, Hebei Chuanghai Biotechnology Co., Ltd. Will continue to uphold the corporate spirit of “integrity, innovation, cooperation, and win-win”, continuously expand business areas, improve service quality, and work hand in hand with global customers to create a better future.
Q1: Quality Assurance
A1:. strictly controls the quality of all products. Every step from raw material sourcing to the final production process adheres to both national and international relevant standards. This rigorous quality – control system ensures that customers receive the highest – quality products.
Q2: Export Experience
A2: i has over 10 years of rich experience in exporting biological products. The company has successfully penetrated more than 100 countries and regions across the globe, including but not limited to Germany, Russia, South Korea, the Philippines, and many others. This extensive international market presence is a testament to the company’s product quality and international competitiveness.
Q3: Lead – time and Freight
A3: For most of the in – stock products, it only takes 1 – 3 workdays to prepare for shipment. When it comes to delivery, using well – known courier services such as DHL, FedEx, and UPS, the delivery time is approximately 3 – 7 business days. The company works with experienced freight forwarders who are capable of arranging shipments with low prices and first – class service, ensuring that the products reach customers in a timely and cost – effective manner.
Q4: Terms of Payment
A4: The company accepts payment via T/T (Telegraphic Transfer). A 30% deposit is required before the mass production of the order, and the remaining 70% balance should be paid before the order is shipped. This payment method provides a certain level of security for both the company and the customers.
Q5: Sample Order
A5: welcomes sample orders. If needed, free samples can be provided to allow customers to test the product quality before placing a large – scale order. This service enables customers to have a better understanding of the company’s products and make more informed purchasing decisions.
