N-methylacetamide is in the form of white needle-shaped crystals or colorless transparent liquid. The specific form may vary depending on temperature, pressure and other conditions.

‌Physical properties‌: The molecular formula of N-methylacetamide is C3H7NO, and the molecular weight is 73.09. Its melting point is usually between 26-28°C, and its boiling point is 204~206°C. It has good water solubility and a density of 0.9571 at 25°C. In addition, its flash point is 108°C, indicating that the substance may be flammable at higher temperatures.
‌Chemical properties and uses‌: N-methylacetamide is chemically stable, not easy to decompose, and has a good ability to dissolve other compounds. It is often used as an organic solvent and can be used as an intermediate in organic synthesis such as pesticides and medicines. In the pharmaceutical production industry, N-methylacetamide is also a commonly used basic raw material, such as for the synthesis of drug molecules cephalosporins.

In summary, N-methylacetamide is mainly in the form of white needle-shaped crystals or colorless transparent liquid. It has a variety of physical and chemical properties and is widely used in organic synthesis and drug production.

‌Applications of N-methylacetamide‌

‌Organic solvent‌: N-methylacetamide is a colorless and transparent liquid at room temperature and pressure. It has good water solubility and is an organic solvent with good chemical stability. It is not easy to decompose and can dissolve a variety of compounds. It is widely used in organic synthesis chemistry‌.

‌Organic synthesis intermediate‌: N-methylacetamide is an important organic synthesis intermediate. It can participate in a variety of organic reactions such as alkylation, hydroxylation, and phosphation, and provides key raw materials for organic synthesis of pesticides, medicines, etc.‌

‌Drug production raw materials‌: In the drug production industry, N-methylacetamide is a commonly used basic raw material, for example, it is used to synthesize cephalosporin antibiotics. This type of antibiotic has the characteristics of bactericidal mechanism and strong antibacterial effect, and is widely used in clinical practice‌.

In summary, N-methylacetamide has important applications in organic solvents, organic synthesis intermediates, and drug production raw materials‌

N-Methylacetamide Chemical Properties
Melting point 26-28 °C (lit.)
Boiling point 204-206 °C (lit.)
density 0.957 g/mL at 25 °C (lit.)
vapor pressure 12-3680Pa at 15-113℃
refractive index n20/D 1.433(lit.)
Fp 227 °F
storage temp. Inert atmosphere,Room Temperature
solubility miscible with ethanol, ether, acetone, water, chloroform, benzene
pka 16.61±0.46(Predicted)
form Solid
color Colourless
PH 7 (H2O)
explosive limit 3.2-18.1%(V)
Water Solubility soluble
BRN 1071255
Dielectric constant 178.90000000000001
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey OHLUUHNLEMFGTQ-UHFFFAOYSA-N
LogP -1.05–0.7 at 25℃

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