n,n-dimethylformamide (DMF) is a very important organic solvent with wide applications in many fields. Specifically, its main uses include:
Solvent: DMF is widely used as a solvent in organic synthesis due to its excellent solubility and chemical stability, especially in the fields of polymer chemistry, dyes, medicines, pesticides and other fields.
Reaction medium: In organic synthesis reactions, DMF can be used as a reaction medium to promote the reaction. For example, DMF can be used as a reaction solvent and catalyst in the preparation of certain amides.
Electrolyte solvent: In the field of electrochemistry, DMF is often used as an electrolyte solvent because of its high conductivity and chemical stability, and is used in the preparation of electrochemical devices such as batteries and capacitors.
Analytical Reagents: In chemical analysis, DMF can be used as a stationary solution in gas chromatography to help separate and identify compounds.
Other uses: In addition, DMF can also be used in synthetic leather, artificial leather, film, and raw materials for manufacturing pesticides such as insecticides and herbicides. In the pharmaceutical industry, it can be used to synthesize sulfa drugs, doxycycline and other drugs.
In summary, n,n-dimethylformamide has important applications in many fields due to its unique physical and chemical properties.
N,N-Dimethylformamide Chemical Properties
Melting point -61 °C (lit.)
alpha 0.94 º
Boiling point 153 °C (lit.)
density 0.944 g/mL (lit.)
vapor density 2.5 (vs air)
vapor pressure 2.7 mm Hg ( 20 °C)
refractive index n20/D 1.430(lit.)
Fp 136 °F
storage temp. Store at +5°C to +30°C.
solubility water: miscible
form liquid
pka -0.44±0.70(Predicted)
color APHA: ≤15
Odor Faint, ammonia-like odor detectable at 100 ppm
Relative polarity 0.386
PH 7 (200g/l, H2O, 20℃)
explosive limit 2.2-16%(V)
Odor Threshold 1.8ppm
Water Solubility soluble
Sensitive Hygroscopic
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Post time: Sep-04-2024






