N,N-dimethylformamide is a colorless transparent liquid. It can be mixed with water and most organic solvents except halogenated hydrocarbons, and has good solubility for a variety of organic and inorganic compounds.
N,N-dimethylformamide (DMF) has a wide range of uses, mainly including the following aspects:
1. As an organic solvent:
DMF is an excellent organic solvent that can dissolve a variety of organic and inorganic compounds and has a strong solubility.
In the polymer chemical industry, it is used for wet spinning of synthetic fibers such as polyacrylonitrile fibers, synthesis of polyurethanes, and plastic film making.
2. As a chemical raw material:
DMF is an excellent reaction medium in many chemical reactions, which can reduce the reaction temperature and improve the purity of the product.
In organic synthesis, DMF, as an important intermediate, participates in the synthesis of a variety of organic compounds.
3. Application in the pharmaceutical industry:
DMF is used to synthesize a variety of drugs, such as iodine pyrimidine, doxycycline, cortisone, etc.
The pharmaceutical industry often uses DMF for drug synthesis, especially the synthesis of some complex organic molecules.
4. Applications in other fields:
In the electronics industry, DMF is used to produce capacitor films and printed circuit boards.
It can also be used as an analytical reagent, a solvent for vinyl resins and acetylene, an extractant, and a raw material for the pesticide chlordimeform.
In the petrochemical industry, DMF can be used as a gas absorbent for separating and refining gases.
N,N-Dimethylformamide Chemical Properties
Melting point -61 °C (lit.)
alpha 0.94 º
Boiling point 153 °C (lit.)
density 0.944 g/mL (lit.)
vapor density 2.5 (vs air)
vapor pressure 2.7 mm Hg ( 20 °C)
refractive index n20/D 1.430(lit.)
Fp 136 °F
storage temp. Store at +5°C to +30°C.
solubility water: miscible
form liquid
pka -0.44±0.70(Predicted)
color APHA: ≤15
Odor Faint, ammonia-like odor detectable at 100 ppm
Relative polarity 0.386
PH 7 (200g/l, H2O, 20℃)
explosive limit 2.2-16%(V)
Odor Threshold 1.8ppm
Water Solubility soluble
Sensitive Hygroscopic
λmax λ: 270 nm Amax: 1.00
λ: 275 nm Amax: 0.30
λ: 295 nm Amax: 0.10
λ: 310 nm Amax: 0.05
λ: 340-400 nm Amax: 0.01
Merck 14,3243
BRN 605365
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Post time: Aug-11-2025






