Form and basic properties of p-toluidine

Form: p-toluidine is a colorless, shiny flaky crystal, or a white to light yellow solid, and may also appear in a tan to brown form.
Solubility: Slightly soluble in water, but soluble in a variety of solvents such as ethanol, ether, benzene, and hydrochloric acid.
Other physical properties: Melting point: Usually between 41-46°C 23. Boiling point: 200°C (normal pressure). Density: Relative density is about 0.9619 to 0.973 g/mL (at 25°C). Refractive index: About 1.5534 to 1.5636 34. Flash point: About 86°C or 192°F. p-Toluidine is mainly used as a dye intermediate and an intermediate of the pharmaceutical pyrimethamine in industry, but it should be noted that it is toxic and is a strong methemoglobin former, so it should be used with caution.
In summary, p-toluidine has multiple forms, and its physical properties vary depending on the form and conditions.
Uses of p-toluidine
Analytical reagent: p-toluidine is used as a reagent in analytical chemistry to help perform specific chemical analyses. Dye synthesis: It is an intermediate for many dyes, such as red base GL, methylamine red lake, basic fuchsin, and is widely used in dye synthesis in the textile, printing and other industries. Pharmaceutical intermediate: In the pharmaceutical field, p-toluidine is an intermediate for the drug pyrimethamine, which is essential for the synthesis of drugs. Other applications: p-toluidine can also be used to prepare 1-hydroxy-4-(p-toluidine)-anthraquinone, which is used as a sensitive reagent for the determination of boron and is mainly used for the coloring of polyester fiber pulp.
p-Toluidine, also known as 4-toluidine, is an organic compound with a chemical formula of C7H9N. It is a colorless, shiny flaky crystal, slightly soluble in water, but soluble in ethanol, ether, benzene, and hydrochloric acid. It should be noted that p-Toluidine is toxic, a strong methemoglobin former, and can irritate the bladder and urethra and cause hematuria, so it should be used with caution.

p-Toluidine Chemical Properties
Melting point 41-46 °C(lit.)
Boiling point 200 °C(lit.)
density 0.973 g/mL at 25 °C(lit.)
vapor density 3.9 (vs air)
vapor pressure 0.26 mm Hg ( 25 °C)
refractive index 1.5636
Fp 192 °F
storage temp. Store below +30°C.
solubility Soluble in ethanol, pyridine, diethyl ether, acetone, carbon tetrachloride, methanol, carbon disulfide, oils and dilute acids.
form powder
pka 5.08(at 25℃)
Specific Gravity 0.962
color tan to brown
explosive limit 6.6%
Water Solubility 1.1 g/100 mL
Sensitive Air & Light Sensitive
Merck 14,9536
BRN 471281
Exposure limits TLV-TWA skin 2 ppm (～9 mg/m3) (ACGIH); Suspected Human Carcinogen (ACGIH).
Dielectric constant 4.9800000000000004
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.

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