‌P-Toluidine is mainly used as a dye and pharmaceutical intermediate‌. Specifically, its uses include:

‌Dye intermediates‌: p-Toluidine is an important intermediate for a variety of dyes, such as dye red base GL, methylamine red lake, basic fuchsin, methyl peri-acid and 4-aminotoluene-3-sulfonic acid wait. It is also used in the preparation of triphenylmethane dyes and oxazine dyes‌.
‌Drug intermediates‌: In the pharmaceutical field, p-toluidine is an intermediate of the drug pyrimethamine, and is also used in the preparation of pesticides such as pyrimethamine and other products‌.
‌Other uses‌: p-Toluidine is also used as an analytical reagent and can also be used in organic synthesis. In analytical chemistry, in addition to being a solvent, it is also used as an impregnating liquid for the refractive index of minerals.
In summary, p-toluidine has wide application value in dyes, drugs and other chemical synthesis fields.

p-Toluidine plays an important role as a pharmaceutical intermediate. The following is a detailed explanation:

‌Dye and pharmaceutical intermediates‌: p-Toluidine is mainly used as a dye intermediate and an intermediate for the pharmaceutical pyrimethamine, and plays a key role in the dye industry and pharmaceutical manufacturing‌.

‌Synthesis of various drugs‌: Its derivatives, such as N,N-dimethyl-p-toluidine and N,N-dihydroxyethyl-p-toluidine, have strong pharmacological activity and can be used to synthesize antibiotics, anti-cancer drugs, etc. kind of medicine‌.

‌Wide application‌: p-Toluidine and its derivatives are used as intermediates in drug synthesis and have a wide range of application prospects, not only limited to traditional drugs, but also include more advanced drug synthesis and polymer material production‌.

In summary, p-toluidine, as a drug intermediate, has an important position and wide application value in the pharmaceutical field.

p-Toluidine Chemical Properties
Melting point 41-46 °C(lit.)
Boiling point 200 °C(lit.)
density 0.973 g/mL at 25 °C(lit.)
vapor density 3.9 (vs air)
vapor pressure 0.26 mm Hg ( 25 °C)
refractive index 1.5636
Fp 192 °F
storage temp. Store below +30°C.
solubility Soluble in ethanol, pyridine, diethyl ether, acetone, carbon tetrachloride, methanol, carbon disulfide, oils and dilute acids.
form powder
pka 5.08(at 25℃)
Specific Gravity 0.962
color tan to brown
explosive limit 6.6%
Water Solubility 1.1 g/100 mL
Sensitive Air & Light Sensitive
Merck 14,9536
BRN 471281
Exposure limits TLV-TWA skin 2 ppm (～9 mg/m3) (ACGIH); Suspected Human Carcinogen (ACGIH).
Dielectric constant 4.9800000000000004

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