‌Triethylamine is a colorless oily liquid with a strong ammonia odor and a slight smoke in the air. It is slightly soluble in water, but soluble in organic solvents such as ethanol and ether.

Triethylamine has a wide range of uses, mainly as a solvent, inhibitor, preservative, and can also be used in synthetic dyes. Specifically:

Solvent: Triethylamine is soluble in most organic solvents such as ethanol, ether, and acetone, so it is often used as a component or substitute for these solvents.

Inhibitor and preservative: In some chemical reactions or storage processes, triethylamine can play the role of an inhibitor to prevent the polymerization of substances; at the same time, it can also be used as a preservative to extend the shelf life of substances.

Synthetic dyes: Triethylamine has an important application in dye synthesis and is a key raw material in the synthesis process of some dyes.

Basic catalyst: Triethylamine often participates as an alkaline catalyst in chemical reactions, and its catalytic mechanism involves steps such as protonation, nucleophilic attack, and hydrogen bond formation. For example, triethylamine plays an important catalytic role in Swern oxidation, dehydrohalogenation, Heck reaction, and the reaction of preparing esters and amides from acyl chlorides.

Application in pharmaceuticals:

Neutralizer: used to adjust the acid-base properties of drugs and improve the stability and solubility of drugs.

Catalyst: promote important chemical reactions in the process of drug synthesis and improve the synthesis efficiency and yield of drugs.

Functional group protecting agent: protect specific groups in drug molecules to prevent them from being affected by unnecessary reactions or degradation during the synthesis process.

In summary, triethylamine has a wide range of applications in many fields and is an important organic chemical raw material.

Triethylamine Chemical Properties
Melting point -115 °C
Boiling point 90 °C
density 0.728
vapor density 3.5 (vs air)
vapor pressure 51.75 mm Hg ( 20 °C)
refractive index n20/D 1.401(lit.)
FEMA 4246 | TRIETHYLAMINE
Fp 20 °F
storage temp. Store below +30°C.
solubility water: soluble112g/L at 20°C
pka 10.75(at 25℃)
form Liquid
Specific Gravity 0.725 (20/4℃)
color Clear
PH 12.7 (100g/l, H2O, 15℃)(IUCLID)
Relative polarity 1.8
Odor Strong ammonia-like odor
Odor Type fishy
Odor Threshold 0.0054ppm
explosive limit 1.2-9.3%(V)
Water Solubility 133 g/L (20 ºC)
Merck 14,9666
JECFA Number 1611
BRN 1843166
Henry’s Law Constant 1.79 at 25 °C (Christie and Crisp, 1967)

Contact Information

MIT-IVY INDUSTRY CO., LTD

Chemical  Industry Park,  69 Guozhuang Road, Yunlong District, Xuzhou  City, Jiangsu Province, China    221100

TEL: 0086- 17363307174    FAX:0086-0516-83769139

WHATSAPP:0086- 17363307174    EMAIL:JOYCE@MIT-IVY.COM PURCHASE@MIT-IVY.COM