CAS NO.99-76-3/Methylparaben Manufacturer/Methyl 4- hydroxybenzoate /High quality/Best price/DA 90 DAYS
Quick Details
Product name:Methylparaben
CAS: 99-76-3
Molecular formula:C8H8O3
Molecular weight:152.15
EINECS No.:202-785-7
Appearance:White or yellowish granular crystals
Other names：Methylparaben;Methyl 4-hydroxybenzoate;:NIPAGIN;NIPAGIN PLAIN;P-HYDROXYBENZOIC ACID METHYL ESTER;RARECHEM AL BF 0098;METHYLPARABEN,FCC;METHYLPARABEN,NF;4-HYDROXYBENZOICACIDMETHYLESTER(METHYLPARABEN);4-HYDROXYLMETHYLBENZOATE;4-Hydroxybenzoic acid, methyl ester;4-(Carbomethoxy)phenol;Methylparaben;4-(Methoxycarbonyl)phenol;Methyl parahydroxybenzoate;Methyl-4-hydroxybenzoate;p-Hydroxybenzoic acid methyl ester;methyl para-hydroxybenzoate;4-Hydroxybenzoic Acid Methyl Ester;Methyl 4-hydroxybenzoate;4-Hydroxy-benzoic acid methyl ester;p-Hydroxybenzoic acid, methyl ester;p-Hydroxybenzoic methyl ester;4-Hydroxybenzoic acid methylester
Port: any port in china
Density:1.209 g/cm3
PSA:46.53000 LogP:1.17880
Solubility:Slightly soluble in water
Melting Point 125-128 °C(lit.)
Boiling Point:265.5 °C at 760 mmHg
Molecular Weight:152.15 Flash Point:116.4 °C
Safety 26-36-24/25 Risk Codes 36/37/38-20/21/22
Packing: according to the clients requirement
Storage: Store in dry, dark and ventilated place.
Transportation: by sea or by air
payment methods: L/C, T/T, D/A, D/P, O/A, paypal, western union etc.accept all payment.
Methylparaben Specification
The Methylparaben, with the CAS registry number 99-76-3, is also known as Methyl p-hydroxybenzoate; 4-(Methoxycarbonyl)phenol.It belongs to the product categories of Developer;Functional Materials;Aromatics.Its EINECS number is 202-785-7.This chemical's molecular formula is C8H8O3 and molecular weight is 152.15. What's more,Its systematic name is Benzoic acid,4-hydroxy-,methyl ester.Methylparaben is readily absorbed from the gastrointestinal tract or through the skin. It is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted without accumulation in the body. In a population with normal skin, methylparaben is practically non-irritating and non-sensitizing; however, allergic reactions to ingested parabens have been reported. It can be found in many of the leading skin/face products.
Physical properties about Methylparaben are: (1)ACD/LogP: 1.882; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.88; (4)ACD/LogD (pH 7.4): 1.83; (5)ACD/BCF (pH 5.5): 15.83; (6)ACD/BCF (pH 7.4): 14.11; (7)ACD/KOC (pH 5.5): 251.25; (8)ACD/KOC (pH 7.4): 223.85; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 3; (12)Index of Refraction: 1.547; (13)Molar Refractivity: 39.908 cm3; (14)Molar Volume: 125.756 cm3; (15)Surface Tension: 45.7929992675781 dyne/cm; (16)Density: 1.21 g/cm3; (17)Flash Point: 116.398 °C; (18)Enthalpy of Vaporization: 52.377 kJ/mol; (19)Boiling Point: 265.536 °C at 760 mmHg; (20)Vapour Pressure: 0.00600000005215406 mmHg at 25°C;
Uses of Methylparaben: Methylparaben is known to slow Drosophila growth rate in the larval and pupal stages. It is an antifungal that is widely used as a preservative for food, drugs, and cosmetics. Mycocten, and is commonly used as an anti-fungal agent in Drosophila food media.Methylparaben is an anti-fungal agent often used in hair gels. The compound is often found in carpules of local anaesthetic, acting as a bacteriostatic agent and preservative. Methylparaben (also called Nipigin M, Tegosept, and Mycocten) is commonly used as a fungicide in Drosophila food media. Usage of methylparaben is known to slow Drosophila growth rate in the larval and pupal stages.
The Methylparaben is harmful by inhalation, in contact with skin and if swallowed. It is Irritating to eyes,respiratory system and skin .when you use it ,wear suitable protective clothing,avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure:
(1)SMILES:COC(=O)c1ccc(cc1)O;
(2)Std. InChI:InChI=1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3;
(3)Std. InChIKey:LXCFILQKKLGQFO-UHFFFAOYSA-N.
The toxicity data of Methylparaben as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 3gm/kg (3000mg/kg) | FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 81, 1974. | |
| mouse | LD50 | intraperitoneal | 960mg/kg (960mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)BEHAVIORAL: ATAXIA
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956. |
| mouse | LD50 | oral | > 8gm/kg (8000mg/kg) | BEHAVIORAL: ATAXIAPERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956. |
| mouse | LD50 | subcutaneous | 1200mg/kg (1200mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 128, Pg. 135, 1960. | |
| rabbit | LD50 | oral | 6gm/kg (6000mg/kg) | FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 81, 1974. | |
| rat | LD50 | subcutaneous | > 500mg/kg (500mg/kg) | Clinical Toxicology. Vol. 4(2), Pg. 185, 1971. |
检验报告
CERTIFICATE OF ANALYSIS
| Product:
对羟基苯甲酸甲酯 Methyl 4- hydroxybenzoate |
CAS:99-76-3 | Inspect Date:2023.02.02 | Production Date:2023.02.01 |
| Molecular formula：C8H8O3 Molecular weight：151.1399 | Quantity：25T | Batch No.:
HC/2302001 |
Shelf life:36 months |
|
检测项目 Test Item And Results |
|||
|
Item |
Specification |
Result |
|
|
外观 Appearance |
白色或类白色结晶性粉末Whiteor almost white crystalline powder |
合格 Qualified |
|
|
含量%≥ aniline assay |
≥98.0-102.0% |
99.65 |
|
|
熔点（℃） Melting Point |
125-128℃ |
126.5 |
|
|
酸度(PH) Acidity |
4-7 |
6.52 |
|
|
干燥失重 Loss on Drying |
≤0.5% |
0.39 |
|
|
灼烧残渣 Ignition Residue |
≤0.1% |
0.05 |
|
|
Conclusion |
Qualified |
||
Application
1. Used as an antifungal agent for food, cosmetics and medicine
2. Used as a preservative, also used in medicine and organic synthesis
3. Preservatives; antimicrobial agents.
4. It is used as antiseptic and fungicide for medicine in the pharmaceutical industry, and also used as antiseptic additive for organic synthesis and food, spices, films, etc.
Superiority
1.supply sample
2.the packing can be according the customers` requirment
3.any inquiries will be replied within 24 hours
4.we provide commerical invoice, packing list, bill of loading, coa , health certificate and origin certificate. if your markets have any special requirements, let us know.
5.factory price.
6.prompt delivery. we have good cooperation with many professional forwarders, we can send the products to you once you confirm the order.
7.we can accept various payment methods, l/c, t/t, d/a, d/p, o/a, paypal, western union etc., and we cooperate with sinosure many years.
Anyway ,if you need any chemicals from China ,MIT -IVY INDUSTRY CO.,LTD can help you.
Company Information
MIT-IVY INDUSTRY CO.,LTD is a manufacturer and exporter of fine chemical dyes & pharmaceutical intermediates in China.
Mainly produce aniline series products ,chlorine series products,and epoxy curing agent
MIT –IVY Industry supplier of Fine chemicals， N-alkylated aniline series products ，organic intermediates.& specialty chemicals ,Leading products N- methyl aniline series, N- ethyl aniline series annual output of tens of thousands of tons. We provide with quality products, timely delivery, technology and best in-class services . Our company with mature technology, reliable quality products in the domestic and foreign markets enjoy a certain reputation. We know only by delivering you the solution and solving the problem, we can make our profit. With excellent product quality, product consistency and strict safety and environmental protection controls, we have made our name throughout the world.MIT-IVY INDUSTRY has been working closely with many global chemical companies such as Archroma, BASF,Indulor Sun Chemical and etc.
We are a company full of vitality. The company has a group of energetic, well-trained employees and strong technical research and development capabilities. We specialize in the production, development and sales of API intermediates, fine chemicals and plant extracts. Relying on advanced equipment and strict management, adhere to the business philosophy of "openness, tolerance, innovation, and sharing" to create a win-win cooperationplatform.Everything comes from innovation, it is our philosophy !
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FAQ
Q1:Will you supply samples for testing?
A: For most of our products, samples are available, but please cover the shipping cost.
Q2:What's your MOQ?
A: For the high value product, our MOQ starts from 10g,100g and 1kg.
Q3:Which kind of payment terms do you accept?
A: Proforma invoice enclosed with our bank information will be sent after confirmation of order.
payment methods: L/C, T/T, D/A, D/P, O/A, paypal, western union etc.accept all payment.
Q4:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem near to zero.
If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Main products
| Mit-Ivy is a well-known fine chemicals and pharmaceutical intermediates manufacturer with strong R&D support in China. Mainly involved Aniline, Chlorine products. Payment：DA 60 DAYS TEL:008613805212761 E-MAIL:info@mit-ivy.com http://www.mit-ivy.com |
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| 产品 | Product | CAS |
| N-甲基间甲苯胺 | N-Methyl-M-Methylaniline | 696-44-6 |
| N-羟乙基苯胺 | N-(2-hydroxyethyl)-Aniline | 122-98-5 |
| N-乙基对甲苯胺 | N-ethyl-p-toluidine | 622-57-1 |
| N,N-二甲基邻甲苯胺 | N,N-Dimethyl-o-toluidine | 609-72-3 |
| N-甲基邻甲苯胺 | N-Methyl-o-methylaniline | 611-21-2 |
| N,N-二乙基对甲苯胺 | N,N-Diethyl-p-toluidine | 613-48-9 |
| N,N-二乙基间甲苯胺 | N,N-diethyl-m-toluidine | 91-67-8 |
| N-氰乙基－N-羟乙基间甲苯胺 | N-cyanoethyl-n-hydroxyethyl-m-toluidine | 119-95-9 |
| N-乙基间甲苯胺 | N-ethyl-m-toluidine | 102-27-2 |
| N-氰乙基－N-羟乙基苯胺 | N-cyanoethyl-n-hydroxyethyl aniline | 92-64-8 |
| N-乙基邻甲苯胺 | N-ethyl-o-toluidine | 94-68-8 |
| N,N-二羟乙基对甲苯胺 | N,N-dihydroxyethyl-p-toluidine | .3077-12-1 |
| N,N-二乙基苯胺 | N,N-diethyl aniline | 91-66-7 |
| N-丁基－N-羟乙基苯胺 | N-butyl-n-hydroxy aniline | 3046-94-4 |
| N-乙基－N-氰乙基间甲苯胺 | N-ethyl-n-cyanoethyl-m-toluidine | 148-69-6 |
| N-丁基－N-氰乙基苯胺 | N-butyl-n-cyano aniline | 61852-40-2 |
| N-甲基－ N-羟乙基苯胺 | N-methyl-n-hydroxyetjyl aniline | 93-90-3 |
| N,N-二丁基苯胺 | N,N-dibutyl aniline | 613-29-6 |
| N-乙基－N-氰乙基苯胺 | N-ethyl-n-cyanoethyl aniline | 148-87-8 |
| N-正丁基苯胺 | N-Phenyl-N-butyl aniline | 1126-78-9 |
| N-乙基－N-羟乙基苯胺 | N-ethyl-n-hydroxyethyl aniline | 92-50-2 |
| N-乙基－N-苄基间甲苯胺 | N-ethyl-n-benzyl-m-toluidine | 119-94-8 |
| N-甲基－N-苄基苯胺 | N-methyl-n-benzyl aniline | 614-30-2 |
| N-异丙基苯胺 | N-isopropy aniline | 768-52-5 |
| N-乙基－N-苄基苯胺 | N-ethyl-n-benzyl aniline | 92-59-1 |
| N-环已基苯胺 | N-Cyclohexylaniline | 1821-36-9 |
| N,N-二甲基间甲苯胺 | N,N,3-trimethyl- Dimethyl-m-toluidine | 121-72-2 |
| N-甲基甲酰苯胺 | N-Methylformanilide | 93-61-8 |
| N-甲基-N-羟乙基对甲苯胺 | N-(2-HYDROXYETHYL)-N-METHYL-4-TOLUIDINE | 2842-44-6 |
| N,N-二甲基对甲苯胺 | N,N,4-trimethyl-;dimethyl-4-toluidine; Dimethyl-p-toluidine |
99-97-8 |
| N-甲基对甲苯胺 | N-Methyl-p-toluidine | 623-08-5 |
| N,N-二甲基苯胺 | N,N-dimethyl aniline | 121-69-7 |
| N,N-二羟乙基苯胺 | N,N-dihydroxyethyl aniline | 120-07-0 |
| N-乙基-N-羟乙基间甲苯胺 | N-Ethyl-N-Hydroxyethyl-M-Toluidine | 91-88-3 |
| N,N-二羟乙基间甲苯胺 | N,N-dihydroxyethyl-m-toluidine | 91-99-6 |
| N-乙基苯胺 | N-ethyl aniline | 103-69-5 |
| N-甲基苯胺 | N-methyl aniline | 100-61-8 |
| N-甲基对甲苯胺 | 4-Methyl-N-methylaniline | 623-08-5 |
| N-甲基-N-羟乙基苯胺 | 2-(N-Methylanilino)ethanol | 93-90-3 |
| N,N-二甲基对苯二胺 | N,N-DIMETHYL-P-PHENYLENEDIAMINE | 99-98-9 |
| 3-(甲氨基)甲苯 | 3-(Methylamino)toluene | 696-44-6 |
| N,N-二异丙醇对甲苯胺 | DIPROPOXY-P-TOLUIDINE | 38668-48-3 |
| N,N-二乙基邻甲苯胺 | N,N-DIETHYL-O-TOLUIDINE | 606-46-2 |
| N-甲基对硝基苯胺 | N-Methyl-4-nitroaniline | 100-15-2 |
| N,N-二苄基苯胺 | N,N-DIBENZYLANILINE | 91-73-6 |
| N-苯基乙醇胺 | 2-Anilinoethanol | 122-98-5 |
| N-苄基苯胺 | N-Phenylbenzylamine | 103-32-2 |
| N-羟乙基间甲苯胺 | N-2-HYDROXYETHYL-M-TOLUIDINE | 102-41-0 |
| N-乙基N氯乙基间甲苯胺 | N-ETHYL-N-CHLOROETHYL-M-TOLUIDINE | 22564-43-8 |
| N,N-二乙基-4-氨基-2-甲基苯甲醛 | 4-Diethylamino-2-methylbenzaldehyde | 92-14-8 |
| 间甲苯胺 | M-Toluidine MT | 108-44-1 |
| 1,4-二溴-2,5-二碘苯 | 1,4-DIBROMO-2,5-DIIODOBENZENE | 63262-06-6 |
| N,N-二羟乙基对苯二胺硫酸盐 | N,N-Bis(2-hydroxyethyl)-p-phenylenediamine sulphate | 54381-16-7 |
| N-乙基-N-苄基-4-氨基苯甲醛 | 4-(N-Ethyl-N-benzyl)amino-benzoaldehyde | 67676-47-5 |
| N,N-二乙基-4-氨基苯甲醛 | 4-Diethylaminobenzaldehyde | 120-21-8 |
| 对二甲胺基苯甲醛 | p-Dimethylaminobenzaldehyde | 100-10-7 |
| 2-氨基噻唑 | 2-Aminothiazole | 96-50-4 |
| 对甲苯胺 | P-Toluidine PT | 106-49-0 |
| N,N-双(2-羟基丙基)苯胺 | N,N-BIS(2-HYDROXYPROPYL)ANILINE | 3077-13-2 |
| N-乙基-N-氰乙基苯胺 | 3-Ethylanilinopropiononitrile | 148-87-8 |
| N-乙基-N-(3'-磺酸苄基)苯胺 | N-Ethyl-N-benzylaniline-3'-sulfonic acid | 101-11-1 |
| 邻苯甲酰苯甲酸甲酯 | Methyl 2-benzoylbenzoate | 606-28-0 |
| 对羟基苯甲酸甲酯 | Methylparaben | 99-76-3 |
| 十四酸异丙酯 | Isopropyl myristate | 110-27-0 |
| 棕榈酸异丙酯 | Isopropyl palmitate | 142-91-6 |
| 邻甲苯胺 | O-Toluidine OT | 95-53-4 |
| 4-甲基-N-苯基苯胺 | N-PHENYL-P-TOLUIDINE | 620-84-8 |
| N,N-二甲基苄胺 | N,N-Dimethylbenzylamine BDMA | 103-83-3 |
| N,N-二甲基甲酰胺 | N,N-Dimethylformamide DMF | .68-12-2 |
| N-甲基甲酰胺 | N,N-Dimethylformamidedimethyl acetal (DMF-DMA) | 4637-24-5 |
| N,N-二甲基乙酰胺 | N,N-Dimethylacetamide DMAC | 127-19-5 |
| N,N-二乙基间甲苯甲酰胺 避蚊胺 |
N,N-diethyl-m-toluamide DEET | 134-62-3 |
| N,N-二乙基羟胺 | N,N-Diethylhydroxylamine DEHA | 3710-84-7 |
| N,N-二甲基-间甲基苯胺 | N,N-DIMETHYL-M-TOLUIDINE | 121-72-2 |
| N-甲基二苯胺 | N-Methyldiphenylamine | 552-82-9 |
| N,N-二氰乙基苯胺 | N,N-Dicyanoethylaniline | 1555-66-4 |
| N-乙基-2-硝基苯胺 | N-Ethyl-2-Nitro-Benzenamine | 10112-15-9 |
| N-(2-羟乙基)乙二胺 | AEEA | 111-41-1 |
| 二乙烯三胺(DETA) | Diethylenetriamine DETA | 111-40-0 |
| 三乙烯二胺 | Triethylenediamine | 280-57-9 |
| 三乙烯四胺 | TriethylenetetramineTETA | 112-24-3 |
| 四乙烯五胺 | TEPA | 112-57-2 |
| 间二氯苯 | 1,3-Dichlorobenzene MDCB | 541-73-1 |
| 间二三氟甲苯 | 1,3-Bis(trifluoromethyl)-benzene | 402-31-3 |
| 粉末丁腈橡胶 | MITIVY33-1（POLYMER/ADHESIVE COMPOUNDING） | 9003-18-3 |
| 十六烷基氯化吡啶 | Cetylpyridinium chloride monohydrate | 6004-24-6 |
| 对氯甲苯 | 4-Chlorotoluene | 106-43-4 |
| 无水硫酸钠 | SODIUM SULFATE | 7757-82-6 /15124-09-1 |
| 碱性嫩黄 | Auramine O | 2465-27-2 |
| 偶氮二异丁腈 | 2,2'-Azobis(2-methylpropionitrile) | 78-67-1 |
